San Diego Loyal SC lost to Seattle Sounders FC in the U.S. Open Cup, 5-4. The match took place on April 26, 2023, at Starfire Sports Stadium in Tukwila, Washington. Seattle Sounders FC took the lead early in the game with a goal from Fredy Montero in the 15th minute. San Diego Loyal SC responded with a goal from Ethan Dobbelaere in the 26th minute. The first half ended with Seattle Sounders FC leading 1-1. In the second half, Seattle Sounders FC took the lead again with a goal from Joe Corona in the 53rd minute. San Diego Loyal SC responded with a goal from Reed Baker-Whiting in the 73rd minute. The match ended with Seattle Sounders FC winning 5-4. Fredy Montero scored two goals for Seattle Sounders FC, while Reed Baker-Whiting scored one goal for San Diego Loyal SC.